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ESPN College GameDay is on site for Oregon at Penn State, and they made their picks of Week 5 games including Notre Dame at Arkansas.

Notre Dame will take on Arkansas, but ESPN’s College GameDay had plenty of other options to be in attendance, and they’re in State College as the Oregon Ducks take on the Penn State Nittany Lions.

The regular crew of Desmond Howard, Nick Saban, Pat McAfee, and Kirk Herbstreit were joined by Nittany Lions linebacker legend LaVar Arrington to make the picks of the biggest games of the day. Find out below who each of them picked to win the biggest games along with Notre Dame at Arkansas.

No. 1 Ohio State Buckeyes at Washington Huskies

Teammates celebrate a touchdown by Ohio State Buckeyes tight end Max Klare (86) during the NCAA football game against the Ohio Bobcats at Ohio Stadium on Sept. 13, 2025. Ohio State won 37-9.

Howard - Ohio State

Saban - Ohio State

Arrington - Washington

McAfee - Ohio State

Herbstreit - Ohio State

Arizona Wildcats at No. 14 Iowa State Cyclones

Iowa State Cyclones defense celebrates after a fourth down stop as clinched win 16-13 over Iowa in the Cy-Hawk football at Jack Trice Stadium on Sept. 6, 2025, in Ames, Iowa

Howard - Iowa State

Saban - Iowa State

Arrington - Iowa State

McAfee - Iowa State

Herbstreit - Iowa State

No. 21 USC Trojans at No. 23 Illinois Fighting Illini

Sep 20, 2025; Los Angeles, California, USA; Southern California Trojans quarterback Jayden Maiava (14) following the victory against the Michigan State Spartans at the Los Angeles Memorial Coliseum. Mandatory Credit: Gary A. Vasquez-Imagn Images

Howard - USC

Saban - USC

Arrington - USC

McAfee - Illinois

Herbstreit - USC

No. 11 Indiana Hoosiers at Iowa Hawkeyes

Sep 20, 2025; Bloomington, Indiana, USA; Indiana Hoosiers linebacker Quentin Clark (40) and Indiana Hoosiers wide receiver Elijah Sarratt (13) celebrate after defeating the Illinois Fighting Illini at Memorial Stadium. Mandatory Credit: Robert Goddin-Imagn Images

Howard - Indiana

Saban - Indiana

Arrington - Iowa

McAfee - Indiana

Herbstreit - Indiana

No. 22 Notre Dame Fighting Irish at Arkansas Razorbacks

Notre Dame wide receiver Jordan Faison (6) celebrates after scoring a touchdown during the second half of a NCAA football game against Purdue at Notre Dame Stadium on Saturday, Sept. 20, 2025, in South Bend.

Howard - Notre Dame

Saban - Notre Dame

Arrington - Notre Dame

McAfee - Notre Dame

Herbstreit - Notre Dame

No. 15 Tennessee Volunteers at Mississippi State Bulldogs

Sep 20, 2025; Knoxville, Tennessee, USA; Tennessee Volunteers defensive back Kaleb Beasley (10) celebrates after returning a fumble for a touchdown against the UAB Blazers during the second half at Neyland Stadium. Mandatory Credit: Randy Sartin-Imagn Images

Howard - Mississippi State

Saban - Tennessee

Arrington - Tennessee

McAfee - Tennessee

Herbstreit - Tennessee

Auburn Tigers at No. 9 Texas A&M Aggies

Texas A&M tight end Nate Boerkircher (87) celebrates after scoring a touchdown to tie the game in the second half of a NCAA football game against Notre Dame at Notre Dame Stadium on Saturday, Sept. 13, 2025, in South Bend. The extra point scored after this touchdown put Texas A&M ahead 41-40 to win the game.

Howard - Texas A&M

Saban - Texas A&M

Arrington - Texas A&M

McAfee - Texas A&M

Herbstreit - Texas A&M

No. 4 LSU Tigers at No. 13 Ole Miss Rebels

Sep 20, 2025; Oxford, Mississippi, USA; Mississippi Rebels defensive back Cedrick Beavers (13) dunk on a basketball goal after an interception during the fourth quarter against the Tulane Green Wave at Vaught-Hemingway Stadium. Mandatory Credit: Petre Thomas-Imagn Images

Howard - Ole Miss

Saban - LSU

Arrington - Ole Miss

McAfee - Ole Miss

Herbstreit - LSU

No. 17 Alabama Crimson Tide at No. 5 Georgia Bulldogs

Sep 13, 2025; Knoxville, Tennessee, USA; Georgia Bulldogs tight end Lawson Luckie (7) reacts after the game against Tennessee Volunteers at Neyland Stadium. Mandatory Credit: Alan Poizner-Imagn Images

Howard - Georgia

Saban - Alabama

Arrington - Georgia

McAfee - Georgia

Herbstreit - no pick

No. 6 Oregon Ducks at No. 3 Penn State Nittany Lions

Sep 13, 2025; University Park, Pennsylvania, USA; Penn State Nittany Lions running back Kaytron Allen (13) runs with the ball which would result in a touchdown during the fourth quarter against the Villanova Wildcats at Beaver Stadium. Mandatory Credit: Matthew O'Haren-Imagn Images

Howard - Oregon

Saban - Penn State

Arrington - Penn State

McAfee - Penn State

Herbstreit - Penn State

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This article originally appeared on Fighting Irish Wire: ESPN College GameDay picks Notre Dame at Arkansas and top Week 5 games

Category: General Sports