Gibbs, Achane lead Week 5 fantasy football running back rankings

Jahmyr Gibbs and De'Von Achane lead UPI senior sports writer Alex Butler's Top-50 fantasy football running back rankings for Week 5 of the 2025 season.

Detroit Lions running back Jahmyr Gibbs leads my Week 5 fantasy football running back rankings. File Photo by David Tulis/UPI
Detroit Lions running back Jahmyr Gibbs leads my Week 5 fantasy football running back rankings. File Photo by David Tulis/UPI

MIAMI, Oct. 1 (UPI) -- Jahmyr Gibbs and De'Von Achane lead my Top-50 fantasy football running back rankings for Week 5 of the 2025 season.

Christian McCaffrey, Jonathan Taylor and Saquon Barkley join Gibbs and Achane inside my Top 5. Omarion Hampton, James Cook, Ashton Jeanty, Derrick Henry and Travis Etienne are my other Top-10 options.

My Top-50 wide receiver rankings for Week 5 can be found here. My waiver-wire and free agent targets for Week 5 are available here.

All of my positional rankings will be updated until Week 5 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.

Be sure to monitor your lineups for injury developments. Players from the Atlanta Falcons, Chicago Bears, Green Bay Packers and Pittsburgh Steelers, who are on bye, should not be in starting lineups.

Miami Dolphins running back De'Von Achane (C) is an elite fantasy football RB1. File Photo by Kevin M. Cox/UPI
Miami Dolphins running back De'Von Achane (C) is an elite fantasy football RB1. File Photo by Kevin M. Cox/UPI

Week 5 running back rankings

1. Jahmyr Gibbs, Detroit Lions at CIN

Minnesota Vikings running back Jordan Mason (L) can stay in lineups as a fantasy football RB2. File Photo by Mark Black/UPI
Minnesota Vikings running back Jordan Mason (L) can stay in lineups as a fantasy football RB2. File Photo by Mark Black/UPI

2. De'Von Achane, Miami Dolphins at CAR

3. Christian McCaffrey, San Francisco 49ers at LAR

San Francisco 49ers running back Christian McCaffrey is among my Top 5 fantasy football plays for Week 5. File Photo by Terry Schmitt/UPI
San Francisco 49ers running back Christian McCaffrey is among my Top 5 fantasy football plays for Week 5. File Photo by Terry Schmitt/UPI

4. Jonathan Taylor, Indianapolis Colts vs. LV

5. Saquon Barkley, Philadelphia Eagles vs. DEN

Buffalo Bills running back James Cook is my No. 7 fantasy football running back in Week 5. File Photo by Rena Laverty/UPI
Buffalo Bills running back James Cook is my No. 7 fantasy football running back in Week 5. File Photo by Rena Laverty/UPI

6. Omarion Hampton, Los Angeles Chargers vs. WAS

7. James Cook, Buffalo Bills vs. NE

8. Ashton Jeanty, Las Vegas Raiders at IND

9. Derrick Henry, Baltimore Ravens vs. HOU

10. Travis Etienne, Jacksonville Jaguars vs. KC

11. Quinshon Judkins, Cleveland Browns vs. MIN

12. Javonte Williams, Dallas Cowboys at NYJ

13. Breece Hall, New York Jets vs. DAL

14. Cam Skattebo, New York Giants at NO

15. Kyren Williams, Los Angeles Rams vs. SF

16. Chuba Hubbard, Carolina Panthers vs. MIA

17. J.K. Dobbins, Denver Broncos at PHI

18. Bucky Irving, Tampa Bay Buccaneers at SEA

19. Alvin Kamara, New Orleans Saints vs. NYG

20. Jordan Mason, Minnesota Vikings vs. CLE

21. Chase Brown, Cincinnati Bengals vs. DET

22. David Montgomery, Detroit Lions at CIN

23. Kenneth Walker, Seattle Seahawks vs. TB

24. Woody Marks, Houston Texans at BAL

25. Tony Pollard, Tennessee Titans at ARI

26. Rhamondre Stevenson, New England Patriots at BUF

27. Emari Demercado, Arizona Cardinals vs. TEN

28. R.J. Harvey, Denver Broncos at PHI

29. TreVeyon Henderson, New England Patriots at BUF

30. Isiah Pacheco, Kansas City Chiefs at JAX

31. Zach Charbonnet, Seattle Seahawks vs. TB

32. Rachaad White, Tampa Bay Buccaneers at SEA

33. Michael Carter, Arizona Cardinals vs. TEN

34. Rico Dowdle, Carolina Panthers vs. MIA

35. Bhayshul Tuten, Jacksonville Jaguars vs. KC

36. Chris Rodriguez, Washington Commanders at LAC

37. Nick Chubb, Houston Texans at BAL

38. Justice Hill, Baltimore Ravens vs. HOU

39. Jacory Croskey-Merritt, Washington Commanders at LAC

40. Kendre Miller, New Orleans Saints vs. NYG

41. Ollie Gordon II, Miami Dolphins at CAR

42. Kareem Hunt, Kansas City Chiefs at JAX

43. Zavier Scott, Minnesota Vikings vs. CLE

44. Isaiah Davis, New York Jets vs. DAL

45. Blake Corum, Los Angeles Rams vs. SF

46. Jerome Ford, Cleveland Browns vs. MIN

47. Brian Robinson Jr., San Francisco 49ers at LAR

48. Devin Singletary, New York Giants at NO

49. Jeremy McNichols, Washington Commanders at LAC

50. Raheem Mostert, Las Vegas Raiders at IND

Category: Football