Puka Nacua and Emeka Egbuka lead UPI senior sports writer Alex Butler's Top 50 fantasy football wide receiver rankings for Week 6 of the 2025 NFL season.
MIAMI, Oct. 8 (UPI) -- Puka Nacua and Emeka Egbuka lead my Top-50 fantasy football wide receiver rankings for Week 6.
Amon-Ra St. Brown, Jaxson Smith-Njigba and Rome Odunze join Nacua and Egbuka in my Top 5. Ja'Marr Chase, Davante Adams, George Pickens, Deebo Samuel and A.J. Brown are among my other Top-10 options.
My top free agent targets for Week 6 are available here.
All of my positional rankings will be updated until Week 6 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries. Be sure to monitor your fantasy football team lineups.
Players from the Minnesota Vikings and Houston Texans, who are on bye, should be benched or, in some cases, dropped from rosters. Philadelphia Eagles and New York Giants players, who played Thursday, were also removed from my rankings.
Week 6 wide receiver rankings
1. Puka Nacua, Los Angeles Rams at BAL
2. Emeka Egbuka, Tampa Bay Buccaneers vs. SF
3. Amon-Ra St. Brown, Detroit Lions at KC
4. Jaxson Smith-Njigba, Seattle Seahawks at JAX
5. Rome Odunze, Chicago Bears at WAS
6. Ja'Marr Chase, Cincinnati Bengals at GB
7. Davante Adams, Los Angeles Rams at BAL
8. George Pickens, Dallas Cowboys at CAR
9. Deebo Samuel, Washington Commanders vs. CHI
10. Jaylen Waddle, Miami Dolphins vs. LAC
11. Drake London, Atlanta Falcons vs. BUF
12. Tetairoa McMillan, Carolina Panthers vs. DAL
13. Michael Pittman Jr., Indianapolis Colts vs. ARI
14. Xavier Worthy, Kansas City Chiefs vs. DET
15. Garrett Wilson, New York Jets vs. DEN
16. Zay Flowers, Baltimore Ravens vs. LAR
17. Chris Olave, New Orleans Saints vs. NE
18. Marvin Harrison Jr., Arizona Cardinals at IND
19. Courtland Sutton, Denver Broncos vs. NYJ
20. Ladd McConkey, Los Angeles Chargers at MIA
21. Keenan Allen, Los Angeles Chargers at MIA
22. DK Metcalf, Pittsburgh Steelers vs. CLE
23. Jakobi Meyers, Las Vegas Raiders vs. TEN
24. Brian Thomas Jr., Jacksonville Jaguars vs. SEA
25. Matthew Golden, Green Bay Packers vs. CIN
26. Stefon Diggs, New England Patriots at NO
27. Jauan Jennings, San Francisco 49ers at TB
28. Tee Higgins, Cincinnati Bengals at GB
29. Calvin Ridley, Tennessee Titans at LV
30. Jameson Williams, Detroit Lions at KC
31. Ricky Pearsall, San Francisco 49ers at TB
32. Tre Tucker, Las Vegas Raiders vs. TEN
33. Sterling Shepard, Tampa Bay Buccaneers vs. SF
34. Cooper Kupp, Seattle Seahawks at JAX
35. D.J. Moore, Chicago Bears at WAS
36. Jerry Jeudy, Cleveland Browns at PIT
37. Khalil Shakir, Buffalo Bills at ATL
38. Travis Hunter, Jacksonville Jaguars vs. SEA
39. Rashid Shaheed, New Orleans Saints vs. NE
40. Romeo Doubs, Green Bay Packers vs. CIN
41. Keon Coleman, Buffalo Bills at ATL
42. Malik Washington, Miami Dolphins vs. LAC
43. Isaiah Bond, Cleveland Browns at PIT
44. Marquise Brown, Kansas City Chiefs vs. DET
45. Kendrick Bourne, San Francisco 49ers at TB
46. Tez Johnson, Tampa Bay Buccaneers vs. SF
47. Tory Horton, Seattle Seahawks at JAX
48. Olamide Zaccheaus, Chicago Bears at WAS
49. Elic Ayomanor, Tennessee Titans at LV
50. Marvin Mims, Denver Broncos vs. NYJ
Category: Football
