Get the opening NFL Week 8 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Oct. 23, 2025.
After a wild Sunday, we can look ahead to Week 8 of the 2025 NFL season.
We still have a pair of Monday Night Games to follow, but we could be in for a few high-scoring clashes in the ensuing weekend.
The highest total on the board is 49.5, when the Chicago Bears meet the Baltimore Ravens, who should see Lamar Jackson return to action.
The week starts with a matchup between teams floundering of late as the Los Angeles Chargers host the Minnesota Vikings on Thursday Night Football.
Meanwhile, the Kansas City Chiefs have found new life and are 9.5-point favorites over the Washington Commanders on Monday Night Football.
NFL odds Week 8
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Vikingsvs  Chargers | Chargers -2.5 | Vikings +124 Chargers -146 | 43.5 |
 Jetsvs  Bengals | Bengals -4.5 | Jets +200 Bengals -245 | 44.5 |
 Bearsvs  Ravens | Ravens -6.5 | Bears +265 Ravens -303 | 49.5 |
 Dolphinsvs  Falcons | Falcons -5.5 | Dolphins +220 Falcons -270 | 45.5 |
 Brownsvs  Patriots | Patriots -7 | Browns +260 Patriots -320 | 40.5 |
 Giantsvs  Eagles | Eagles -7 | Giants +280 Eagles -350 | 42.5 |
 Billsvs  Panthers | Panthers +7.5 | Bills -400 Panthers +315 | 47.5 |
 49ersvs  Texans | Texans -1.5 | 49ers +108 Texans -126 | 44.5 |
 Buccaneersvs  Saints | Saints +6.5 | Buccaneers -275 Saints +225 | 47.5 |
 Cowboysvs  Broncos | Broncos -3 | Cowboys +130 Broncos -154 | 48.5 |
 Titansvs  Colts | Colts -14.5 | Titans +700 Colts -1100 | 44.5 |
 Packersvs  Steelers | Steelers +3 | Packers -164 Steelers +138 | 43.5 |
 Commandersvs  Chiefs | Chiefs -9.5 | Commanders +410 Chiefs -550 | 48.5 |
Lines as of 10-19
Vikings vs Chargers odds (Thursday, 8:15 p.m. ET, Prime Video)
Opening line
- Chargers -3.5
- Over/Under 43.5
- View full Vikings vs. Chargers odds and matchup
- Read our Vikings vs. Chargers picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Thursday Night Football odds
Jets vs Bengals odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Bengals -2.5
- Over/Under 41.5
- View full Jets vs. Bengals odds and matchup
- Read our Jets vs. Bengals picks and predictions (coming soon)
Opening line analysis coming soon!
Bears vs Ravens odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Ravens -6.5
- Over/Under 48.5
- View full Bears vs. Ravens odds and matchup
- Read our Bears vs. Ravens picks and predictions (coming soon)
Opening line analysis coming soon!
Covers NFL betting tools
Dolphins vs Falcons odds (Sunday, 1:00 p.m. ET, CBS)
Opening line
- Falcons -5.5
- Over/Under 45.5
- View full Dolphins vs. Falcons odds and matchup
- Read our Dolphins vs. Falcons picks and predictions (coming soon)
Opening line analysis coming soon!
Browns vs Patriots odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Patriots -7
- Over/Under 40.5
- View full Browns vs. Patriots odds and matchup
- Read our Browns vs. Patriots picks and predictions (coming soon)
Opening line analysis coming soon!
Giants vs Eagles odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Eagles -7.5
- Over/Under 40.5
- View full Giants vs. Eagles odds and matchup
- Read our Giants vs. Eagles picks and predictions (coming soon)
Opening line analysis coming soon!
Covers NFL awards analysis
Bills vs Panthers odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Panthers +7.5
- Over/Under 47.5
- View full Bills vs. Panthers odds and matchup
- Read our Bills vs. Panthers picks and predictions (coming soon)
Opening line analysis coming soon!
49ers vs Texans odds (Sunday, 1:00 p.m. ET, FOX)
Opening line
- Texans -1.5
- Over/Under 44.5
- View full 49ers vs. Texans odds and matchup
- Read our 49ers vs. Texans picks and predictions (coming soon)
Opening line analysis coming soon!
Buccaneers vs Saints odds (Sunday, 4:05 p.m. ET, FOX)
Opening line
- Saints +5.5
- Over/Under 47.5
- View full Buccaneers vs. Saints odds and matchup
- Read our Buccaneers vs. Saints picks and predictions (coming soon)
Opening line analysis coming soon!
More NFL betting analysis
- Aaron Rodgers’ record vs. every NFL team
- Patrick Mahomes’ record vs. every NFL team
- Russell Wilson’s record vs. every NFL team
- Josh Allen’s record vs. every NFL team
- Lamar Jackson’s record vs. every NFL team
Cowboys vs Broncos odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Broncos -4.5
- Over/Under 47.5
- View full Cowboys vs. Broncos odds and matchup
- Read our Cowboys vs. Broncos picks and predictions (coming soon)
Opening line analysis coming soon!
Titans vs Colts odds (Sunday, 4:25 p.m. ET, CBS)
Opening line
- Colts -12.5
- Over/Under 44.5
- View full Titans vs. Colts odds and matchup
- Read our Titans vs. Colts picks and predictions (coming soon)
Opening line analysis coming soon!
Packers vs Steelers odds (Sunday, 8:20 p.m. ET, NBC)
Opening line
- Steelers +3
- Over/Under 43.5
- View full Packers vs. Steelers odds and matchup
- Read our Packers vs. Steelers picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Sunday Night Football odds
Commanders vs Chiefs odds (Monday, 8:15 p.m. ET, ABC/ESPN)
Opening line
- Chiefs -6.5
- Over/Under 50.5
- View full Commanders vs. Chiefs odds and matchup
- Read our Commanders vs. Chiefs picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Monday Night Football odds
Best NFL bets this week
Looking for our favorite spread, total, and NFL prop bets for this week's action? Check out our best free NFL picks from the Covers staff!
Odds are correct at the time of publishing and are subject to change.
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Category: Football
