Here's how to watch the Arizona Cardinals and the San Francisco 49ers when they play this Sunday afternoon.
The San Francisco 49ers and the Arizona Cardinals will face off in a divisional clash this Sunday airing on FOX. Both NFC West teams are currently undefeated heading into Week 3. 49ers quarterback Brock Purdy, who has been recovering from injuries he suffered during Week 1, is still unconfirmed to play in Sunday's game but appears hopeful, stating earlier this week, "I'd love to [play], but I mean, I'm trying to be smart with my body here, but you never know. We'll see when the game comes." If Purdy is out, expect to see Mac Jones covering for him.
The Sunday afternoon Cardinals vs. 49ers game will kick off at 4:25 p.m. ET on FOX. (Out-of-market fans can catch the game on YouTube TV's Sunday Ticket, or NFL+.) Here's everything you need to know about how to watch this Sunday's game between the Cardinals and the 49ers, and the full Week 3 schedule for the rest of the league.
How to watch the San Francisco 49ers vs. Arizona Cardinals:
Date: Sunday, Sept. 21
Time: 4:25 p.m. ET
TV channel: FOX
Streaming: DirecTV, YouTube TV via NFL Sunday Ticket (out-of-market), FOX One, Hulu + Live TV, Fubo + more
Arizona Cardinals vs. San Francisco 49ers game time:
The Cardinals vs. 49ers game kicks off at 4:25 p.m. ET/1:25 p.m. PT this Sunday, Sept. 21, 2025.
Arizona Cardinals vs. San Francisco 49ers game channel:
The Week 3 game between the Cardinals and the 49ers will air locally on FOX. Out-of-market, you can tune in via NFL Sunday Ticket on YouTube TV.
How to watch the Arizona Cardinals vs. San Francisco 49ers game without cable:
You can stream FOX on platforms like DirecTV and Fubo, and the game will also be available on FOX's new streaming platform FOX One. Out-of-market fans can tune in with YouTube TV's NFL Sunday Ticket or NFL+ for mobile viewing.
NFL Week 3 schedule:
All times Eastern.
Thursday, Sept. 18, 2025
Dolphins vs. Bills: 8:15 p.m. (Prime Video)
Sunday, Sept. 21, 2025
Steelers vs. Patriots: 1 p.m. (CBS)
Rams vs. Eagles: 1 p.m. (FOX)
Falcons vs. Panthers: 1 p.m. (FOX)
Packers vs. Browns: 1 p.m. (FOX)
Texans vs. Jaguars: 1 p.m. (CBS)
Bengals vs. Vikings: 1 p.m. (CBS)
Jets vs. Buccaneers: 1 p.m. (FOX)
Colts vs. Titans: 1 p.m. (CBS)
Raiders vs. Commanders: 1 p.m. (FOX)
Broncos vs. Chargers: 4:05 p.m.(CBS)
Saints vs. Seahawks: 4:05 p.m. (CBS)
Cowboys vs. Bears: 4:25 p.m. (FOX)
Cardinals vs. 49ers: 4:25 p.m. (FOX)
Chiefs vs. Giants 8:20 p.m. (NBC)
Monday, Sept. 22, 2024
Lions vs. Ravens: 8:15 p.m. (ESPN/ABC)
How to watch NFL games in 2025:
Many NFL games are broadcast on local channels, so if you're looking to catch an in-market game, it may be as simple as turning on your TV (or setting up a digital TV antenna) or finding a live TV streaming service that carries the correct RSN (Regional Sports Network). If you want to watch out-of-market games, a $7 monthly subscription to NFL+ will let you watch every out-of-market-game local and primetime game in the season on your phone — but only a select few regular season games on your TV. You could also spring for the uber-expensive NFL Sunday Ticket package to get every out-of-market Sunday game of the season.
When it comes to nationally broadcast games, NFL games typically air across ESPN, NBC, CBS, Fox, ABC and NFL Network. Thursday Night Football games stream exclusively on Prime Video, select football games will stream exclusively on Peacock, games on CBS will stream live on Paramount+, and Monday Night Football games will air on ESPN or ABC and stream on the newly revamped ESPN+ this season. That's six channels and four streaming platforms to keep up with this season — and that's not counting your local RSN's for in-market games and an NFL+ or NFL Sunday Ticket subscription for out-of-market games. Plus, Netflix is once again hosting at least two Christmas Day matches, so add that subscription into the mix. And we can't forget about Fox One, Fox's first streaming service, a place where you can also stream games airing on FOX (if you don't already have access to it).
Confused? You're not alone. Here's a breakdown of the platforms we recommend checking out ahead of the 2025 NFL season, so that come game time, tuning into your favorite team's games will be as easy as simply turning on the TV.
How to watch NFL games in person:
Tickets for the 2025 NFL season are on sale now.
Find ticketsEvery way to watch NFL games this season:
To recap, here are all the ways you can watch NFL games in 2025.
Category: General Sports
