Mahomes, Goff lead Week 5 fantasy football quarterback rankings

Patrick Mahomes and Jared Goff lead UPI senior sports writer Alex Butler's Top-20 fantasy football quarterback rankings for Week 5 of the 2025 season.

Kansas City Chiefs quarterback Patrick Mahomes calls out coverage against the Ravens at Arrowhead Stadium on Sunday in Kansas City, Mo. Photo by Jon Robichaud/UPI
Kansas City Chiefs quarterback Patrick Mahomes calls out coverage against the Ravens at Arrowhead Stadium on Sunday in Kansas City, Mo. Photo by Jon Robichaud/UPI

MIAMI, Oct. 2 (UPI) -- Patrick Mahomes and Jared Goff lead my Top-20 fantasy football quarterback rankings for Week 5 of the 2025 season.

Justin Herbert, Josh Allen and Justin Fields join Mahomes and Goff inside my Top 5. Jayden Daniels, Jalen Hurts, Dak Prescott, Baker Mayfield and Matthew Stafford are my other Top-10 options.

My Top-50 running back and Top 50 wide receiver rankings for Week 5 can be found here. My waiver-wire and free agent targets for Week 5 are available here.

All of my positional rankings will be updated until Week 5 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.

Be sure to monitor your lineups for injury developments. Quarterbacks from the Atlanta Falcons, Chicago Bears, Green Bay Packers and Pittsburgh Steelers, who are on bye, should not be in starting lineups.

Detroit Lions quarterback Jared Goff (16) is my No. 2 fantasy football option. File Photo by David Tulis/UPI
Detroit Lions quarterback Jared Goff (16) is my No. 2 fantasy football option. File Photo by David Tulis/UPI

Week 5 fantasy football quarterback rankings

1. Patrick Mahomes, Kansas City Chiefs at JAX

Los Angeles Chargers quarterback Justin Herbert remains an elite fantasy football option. File Photo by Jon Robichaud/UPI
Los Angeles Chargers quarterback Justin Herbert remains an elite fantasy football option. File Photo by Jon Robichaud/UPI

2. Jared Goff, Detroit Lions at CIN

3. Justin Herbert, Los Angeles Chargers vs. WAS

Buffalo Bills quarterback Josh Allen is the top-scoring player in fantasy football. File Photo by Jon Robichaud/UPI
Buffalo Bills quarterback Josh Allen is the top-scoring player in fantasy football. File Photo by Jon Robichaud/UPI

4. Josh Allen, Buffalo Bills vs. NE

5. Justin Fields, New York Jets vs. DAL

Los Angeles Rams veteran Matthew Stafford scored the third-most points among fantasy football quarterbacks in Week 4. File Photo by Mark Black/UPI
Los Angeles Rams veteran Matthew Stafford scored the third-most points among fantasy football quarterbacks in Week 4. File Photo by Mark Black/UPI

6. Jayden Daniels, Washington Commanders at LAC

7. Jalen Hurts, Philadelphia Eagles vs. DEN

8. Dak Prescott, Dallas Cowboys at NYJ

9. Baker Mayfield, Tampa Bay Buccaneers at SEA

10. Matthew Stafford, Los Angeles Rams vs. SF

11. Drake Maye, New England Patriots at BUF

12. Kyler Murray, Arizona Cardinals vs. TEN

13. Tua Tagovailoa, Miami Dolphins at CAR

14. Daniel Jones, Indianapolis Colts vs. LV

15. Geno Smith, Las Vegas Raiders at IND

16. Bryce Young, Carolina Panthers vs. MIA

17. Jake Browning, Cincinnati Bengals vs. DET

18. Jaxson Dart, New York Giants at NO

19. C.J. Stroud, Houston Texans at BAL

20. Bo Nix, Denver Broncos at PHI

Category: Football